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Cochrane Reviews from READ-It Partners in the Cochrane Database of Systematic Reviews.

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Latest resources

Covid-19: six million doses of hydroxychloroquine donated to US despite lack of evidence

Director of READ-IT & CIDG Co-ordinating Editor, Paul Garner, is quoted in the recent BMJ article (published 23 March 2020)

Diagnosing tuberculosis,Cochrane Special Collections

Tuberculosis causes more deaths globally than any other infectious disease and is a top 10 cause of death worldwide.

Peer-reviewed article

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Foodborne and Food-Handler Norovirus Outbreaks: A Systematic Review

Norovirus (NoV) is the commonest cause of gastrointestinal disease in the United Kingdom and in many developed countries, causing diarrhea and vomiting in millions of cases worldwide annually. Transmission is most often mediated from person to person.

Peer-reviewed article

Antibiotics for treating scrub typhus

The aim of this Cochrane Review is to find out whether certain antibiotics are more effective in treating scrub typhus. We collected and analysed all relevant studies to answer this question and included seven studies.

Cochrane Systematic Review: UPDATE

Primary antifungal prophylaxis for cryptococcal disease in HIV -positive people

The aim of this Cochrane Review was to find out if taking an antifungal drug regularly, such as fluconazole, prevented HIV‐positive people who have low cluster of differentiation 4 (CD4) cell counts, from getting cryptococcal disease, and what the potential complications were.

Cochrane Systematic Review: UPDATE

Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance

To find out how accurate Xpert® MTB/RIF (Xpert) is for diagnosing extrapulmonary TB and drug resistance. We included eight forms of extrapulmonary TB: tuberculous meningitis and pleural, lymph node, bone or joint, genitourinary, peritoneal, pericardial, and disseminated TB.

Cochrane Systematic Review: NEW

Credit: Photo by Jacob Arthur-Quarm – Ghana

Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease)

The aim of this Cochrane Review was to summarize the evidence for drug treatments for Buruli ulcer.

Cochrane Systematic Review: NEW

Treatment for HIV‐associated cryptococcal meningitis

The aim of this Cochrane Review was to find the best therapy to reduce the risk of death from cryptococcal meningitis in HIV‐positive individuals.

Cochrane Systematic Review: UPDATE

Early versus delayed antiretroviral treatment in HIV‐positive people with cryptococcal meningitis

The aim of this Cochrane Review was to determine whether initiating antiretroviral therapy (ART) within four weeks of cryptococcal meningitis diagnosis resulted in a higher risk of dying or developing other complications than waiting more than four weeks to initiate ART.

Cochrane Systematic Review: UPDATE

Effects of total fat intake on bodyweight in children

What is the relationship between the amount of fat a child eats and their weight and body fat?

Cochrane Systematic Review: NEW

Revision of the ARRIVE guidelines: rationale and scope

In 2010, the NC3Rs published the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines to improve the reporting of animal research. Despite considerable levels of support from the scientific community, the impact on the quality of reporting in animal research publications has been limited. This position paper highlights the strategy of an expert working group established to revise the guidelines and facilitate their uptake.

Peer-reviewed article

Ribavirin for treating Crimean Congo haemorrhagic fever

Crimean Congo haemorrhagic fever (CCHF) is an infection transmitted to humans by tick bites.

Cochrane Systematic Review: NEW

Vaccines for preventing typhoid fever

To assess the effects of vaccines for preventing typhoid fever.

Cochrane Systematic Review: UPDATE

Educational interventions for improving primary caregiver complementary feeding practices for children aged 24 months and under

To assess the effectiveness of educational interventions for improving the complementary feeding (weaning) practices of primary caregivers of children of complementary feeding age, and related health and growth outcomes in infants.

Cochrane Systematic Review: NEW

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