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Cochrane Reviews from READ-It Partners in the Cochrane Database of Systematic Reviews.

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Latest resources

Covid-19: six million doses of hydroxychloroquine donated to US despite lack of evidence

Director of READ-IT & CIDG Co-ordinating Editor, Paul Garner, is quoted in the recent BMJ article (published 23 March 2020)

Diagnosing tuberculosis,Cochrane Special Collections

Tuberculosis causes more deaths globally than any other infectious disease and is a top 10 cause of death worldwide.

Peer-reviewed article

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WHO interim guidelines for the treatment of gambiense human African trypanosomiasis

This document focuses on the management of patients affected by gambiense HAT and constitutes an update to the WHO therapeutic guidance issued in 2013.

Dissemination products

Larviciding to prevent malaria transmission

Evaluating whether larviciding with chemical or microbial insecticides prevents malaria transmission.

Cochrane Systematic Review: NEW

Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations

Esophageal squamous cell carcinoma (ESCC), one of the most aggressive cancers, is endemic in Sub-Saharan Africa, constituting a major health burden.

Peer-reviewed article

Primaquine at alternative dosing schedules for preventing relapse in people with Plasmodium vivax malaria

Primaquine to cure people with Plasmodium vivax malaria: comparing dosing schedules.

Cochrane Systematic Review: NEW

Artemether for severe malaria

Artemether injection for treating people with severe malaria

Cochrane Systematic Review: UPDATE

Rapid initiation of antiretroviral therapy for people living with HIV

To assess the effects of rapid initiation of ART (defined as offering ART within seven days of HIV diagnosis) on treatment outcomes and mortality in people living with HIV (PLWH). We also aim to describe the characteristics of rapid ART interventions used in the included studies.

Cochrane Systematic Review: NEW

A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks—results from the Lassa fever pilot

Infectious disease epidemics are a constant threat, and while we can strengthen preparedness in advance, inevitably, we will sometimes be caught unaware by novel outbreaks.

Peer-reviewed article

Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

To determine the diagnostic accuracy of Xpert MTB/RIF and Xpert Ultra for tuberculosis in adults with presumptive PTB, and for rifampicin resistance in adults with presumptive rifampicin‐resistant tuberculosis or MDR‐TB.

Cochrane Systematic Review: UPDATE

Prevention and treatment of acute malnutrition in humanitarian emergencies: a multi-organisation collaboration to increase access to synthesised evidence

This project was designed to make the evidence from relevant systematic reviews about malnutrition as accessible as possible to support evidence-based decision-making and to guide future research on the prevention and treatment of acute malnutrition in humanitarian emergencies.

Peer-reviewed article

Podcast: Vaccines for preventing rotavirus diarrhoea: vaccines in use

Hanna Bergman, one of the authors based in the Cochrane Response team in London UK, to tell us about the problem and the latest findings for this review.

Indoor residual spraying in communities using insecticide‐treated nets for the prevention of malaria

The aim of this review was to summarize the impact of pyrethroid‐like or non‐pyrethroid‐like IRS on malaria, when implemented in communities that are using ITNs.

Cochrane Systematic Review: NEW

Ready‐to‐use therapeutic food (RUTF) for home‐based nutritional rehabilitation of severe acute malnutrition in children from six months to five years of age

To assess the effects of home‐based RUTF used during the rehabilitation phase of SAM in children aged between six months and five years on recovery, relapse, mortality and rate of weight gain

Cochrane Systematic Review: UPDATE

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