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Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children

The authors of this review evaluated the benefits and harms of balanced solutions for the rapid rehydration of children with severe dehydration due to acute diarrhoea, in terms of time in hospital and mortality compared to 0.9% saline.

Cochrane Systematic Review: NEW

Patient adherence to tuberculosis treatment in the Indian subcontinent: systematic review and meta-synthesis of qualitative research

How well patients adhere to their tuberculosis (TB) treatment influences their recovery and development of drug resistance, but influences on adherence are multiple and often competing. The authors synthesised qualitative studies from a setting in the Indian subcontinent to understand the dimensions and dynamics involved to help inform service provision.

Peer-reviewed article

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Update (22 Jul 2022) Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection

This is the third iteration of this Cochrane living review summarising the accuracy of point‐of‐care antigen tests for detecting current SARS‐CoV‐2 infection. (original version published 26 August 2020).

Cochrane Systematic Review: UPDATE

Podcast: Community views on mass drug administration for filariasis: a qualitative evidence synthesis

Listen to this podcast on community view on mass drug administration (MDA) for filariasis

Resources supporting trustworthy, rapid and equitable evidence synthesis and guideline development: results from the COVID-19 evidence network to support decision-making (COVID-END)

COVID-19 and subsequent infodemic represents an unprecedented global challenge for evidence synthesis and guideline development. The authors present consolidated resources to facilitate trustworthy, rapid and equitable evidence synthesis, health technology assessments and guidelines for public health and clinical practice.

Peer-reviewed article

Updated podcast: How accurate is chest imaging for diagnosing COVID-19?

Lead author of the May 2022 update, Sanam Ebrahimzadeh, from The Ottawa Hospital Research Institute in Canada, describes the latest findings from the review in this podcast.

WHO Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV

The WHO Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV were published in June 2022, and were informed by three 2018 CIDG reviews

Dissemination products

Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection

The authors of this review assessed the effectiveness of water, sanitation, and hygiene interventions for preventing soil‐transmitted helminth infection.

Cochrane Systematic Review: NEW

Update: Ivermectin for preventing and treating COVID‐19

This update of the original Cochrane review published in 2021 explores the effects of ivermectin in preventing and treating COVID-19 infection.

Cochrane Systematic Review: UPDATE

Update: Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria

Authors of this updated Cochrane review concluded that pyronaridine-artesunate is as effective as other antimalarials and is safe in treating uncomplicated cases of an important type of malaria (Plasmodium falciparum).

Cochrane Systematic Review: UPDATE

Updated Podcast: How accurate are symptoms and medical examination to diagnose COVID-19?

This review was first published in June 2020 and the most recent update was published in May 2022. Here, the lead author, Thomas Struyf from the Katholieke Universiteit Leuven in Belgium, tells us about the latest findings.

Update: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19

This review update (original version published 7 July 2020) examines how accurate diagnosis of COVID‐19 is, based on symptoms and signs from medical examination. The review authors were interested in people with suspected COVID‐19, who go to their doctor, outpatient test centres, or hospital.

Cochrane Systematic Review: UPDATE

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin

How accurate is Xpert MTB/XDR for detecting pulmonary tuberculosis and resistance to tuberculosis drugs (i.e. isoniazid, fluoroquinolones, ethionamide, and amikacin) in adults?

Cochrane Systematic Review: NEW

Is routine Vitamin A supplementation still justified for children in Nepal? Trial synthesis findings applied to Nepal national mortality estimates

The WHO has recommended Vitamin A supplementation for children in low- and middle-income countries for many years to reduce child mortality. Nepal still practices routine Vitamin A supplementation. The authors examined the potential current impact of these programs using national data in Nepal combined with an update of the mortality effect estimate from a meta-analysis of RCTs.

Peer-reviewed article

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