In this narrative review the authors examine critical care capacity building in low-income countries from a health systems perspective
This systematic review aimed to assess the effects of implementing policies or interventions that influence the school food environment on children’s health and nonhealth outcomes
How well patients adhere to their tuberculosis (TB) treatment influences their recovery and development of drug resistance, but influences on adherence are multiple and often competing. The authors synthesised qualitative studies from a setting in the Indian subcontinent to understand the dimensions and dynamics involved to help inform service provision.
This review aimed to assess whether the current evidence supports the blanket supplementation of calcium to prevent pre-eclampsia among pregnant women in Nepal
New study finds that monkeypox virus can spread widely within specialist hospital isolation rooms
In this qualitative evidence synthesis review, the authors study the complex configuration of different agents that impact therapy adherence of young people living with perinatal infections of HIV.
Ensuring research integrity of studies included in evidence synthesis is an approach that helps to provide evidence closer to the unbiased truth and improves respect of human rights in evidence synthesis. In this paper, the author team explains the rationale and application of a Research Integrity Assessment tool for randomized controlled trials for the update of a Cochrane Review.
COVID-19 and subsequent infodemic represents an unprecedented global challenge for evidence synthesis and guideline development. The authors present consolidated resources to facilitate trustworthy, rapid and equitable evidence synthesis, health technology assessments and guidelines for public health and clinical practice.
The WHO has recommended Vitamin A supplementation for children in low- and middle-income countries for many years to reduce child mortality. Nepal still practices routine Vitamin A supplementation. The authors examined the potential current impact of these programs using national data in Nepal combined with an update of the mortality effect estimate from a meta-analysis of RCTs.
This systematic review was conducted with the hypothesis that underdiagnosis is largely secondary to patient drop out along the diagnostic and care pathway.
Road traffic crashes (RTCs) are among the eight leading causes of death globally. Strategies and policies have been put in place by many countries to reduce RTCs and to prevent RTCs and related injuries/deaths.
Refugees, and other forcibly displaced people, face mental distress and may be disproportionately affected by risk factors for suicide. Little is known about suicidal behaviour in these highly-mobile populations because collecting timely, relevant, and reliable data is challenging.
This review evaluated the outcomes for the components of the ACF campaign against the NTEP’s minimum indicators and elicited the challenges faced in implementation.
This is the 24th in the ongoing series of articles describing the GRADE approach for assessing the certainty of a body of evidence in systematic reviews and health technology assessments and how to move from evidence to recommendations in guidelines
When do we have enough qualitative research on a topic?
Knowing whether human corpses can transmit plague will inform policies for handling the bodies of those who have died of the disease. Literature was analyzed to evaluate risk for transmission of Yersinia pestis, the causative agent of plague, from human corpses and animal carcasses.
Using diagrams to help the reader go straight to the essence of a systematic review.
This review aims to make sense of existing qualitative evidence syntheses that explore the barriers and facilitators of adherence to antiretroviral treatment.
This article describes the approach, experiences and lessons learnt from converting a face- to- face workshop to a 6- week online course designed for healthcare professionals in Africa.
Internationally, there are conflicting recommendations regarding the use of facemasks by asymptomatic personnel in long-term care facilities for primary prevention (when no cases have yet been identified) of COVID-19 infection.
Reviewing multiple streams of evidence regarding the benefits and harms of ventilation techniques for coronavirus infections, including that causing COVID-19.
In response to the COVID-19 pandemic, evidence was needed to inform strategies for limiting COVID-19 transmission on public transport.
Director of READ-IT & CIDG Co-ordinating Editor, Paul Garner, is quoted in the recent BMJ article (published 23 March 2020)
This paper describes the TRANSFER Approach, a novel approach for supporting collaboration between review authors and stakeholders from the beginning of the review process to systematically and transparently consider factors that may influence the transferability of systematic review findings.
Health policy and systems research (HPSR) guides health system reforms and is essential for South Africa (SA)’s progress towards universal coverage of high-quality healthcare.
The circumstances of people living in refugee camps means that they have distinct medical care requirements. Our objective is to describe clinical guidance in published WHO guidelines that refer to people living in refugee camps; and how evidence and context are used and reported in making recommendations.
Esophageal squamous cell carcinoma (ESCC), one of the most aggressive cancers, is endemic in Sub-Saharan Africa, constituting a major health burden.
Infectious disease epidemics are a constant threat, and while we can strengthen preparedness in advance, inevitably, we will sometimes be caught unaware by novel outbreaks.
This project was designed to make the evidence from relevant systematic reviews about malnutrition as accessible as possible to support evidence-based decision-making and to guide future research on the prevention and treatment of acute malnutrition in humanitarian emergencies.
This Special Collection has been superceded, and the latest version was published 24 March 2020
Tuberculosis (TB) causes more deaths globally than any other infectious disease and is a top 10 cause of death worldwide.
To develop a set of evidence-based recommendations for patient blood management (PBM) and for research.
Most studies evaluating the effect of Xpert MTB/RIF testing for tuberculosis (TB) concluded that it did not reduce overall mortality compared to usual care. We conducted a systematic review to assess whether key study design and execution features contributed to earlier identification of patients with TB and decreased pre-treatment loss to follow-up, thereby reducing the potential impact of Xpert MTB/RIF testing.
Research turnover in the HIV field is rapid, and as a result, maintaining high-quality, up-to-date, and relevant systematic reviews is a challenge. One approach is to frequently update published reviews.
The objective of this article is to describe the development and application of a sampling framework for a qualitative evidence synthesis on vaccination communication.
This analysis provides a practical theory, arising from thematic synthesis of research, to help understand the dynamics of adherence to ART and engagement in HIV care. This can contribute to the design of service delivery approaches, and informed thinking and action on the part of policy makers, providers, and society: to understand what it is to be HIV-positive in Africa and how attitudes and the health service need to shift to help those with HIV lead ‘normal’ lives.
Dialogue and exchange between researchers and policy personnel may increase the use of research evidence in policy
The objective of this article is to examine whether regional biomedicaljournals in Africa had policies on plagiarism and procedures to detect it; and to measure the extent ofplagiarism in their original research articles and reviews.
The aim of this review was to assess the contribution of particular foods to definitively foodborne outbreaks of norovirus (NoV), and to describe the contribution of food handlers to NoV outbreaks.
In 2010, the NC3Rs published the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines to improve the reporting of animal research. Despite considerable levels of support from the scientific community, the impact on the quality of reporting in animal research publications has been limited. This position paper highlights the strategy of an expert working group established to revise the guidelines and facilitate their uptake.