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Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV

The aim of this review was to determine whether the use of LF‐LAM testing had an effect on death and other patient‐important outcomes in people living with HIV.

Cochrane Systematic Review: NEW

Podcast: Ivermectin for preventing and treating COVID-19

Researchers from the COVID-19 Evidence Ecosystem (CEOsys) project collaborated with the LSTM-based Cochrane Infectious Disease Group (CIDG) to carry out a systematic review, to explore the effects of ivermectin in preventing and treating COVID-19 infection.

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Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas

To summarize the effects of public health programmes to regularly treat all children with deworming drugs on child growth, haemoglobin, cognition, school attendance, school performance, physical fitness, and mortality.

Cochrane Systematic Review: UPDATE

WHO guidance for refugees in camps: systematic review

The circumstances of people living in refugee camps means that they have distinct medical care requirements. Our objective is to describe clinical guidance in published WHO guidelines that refer to people living in refugee camps; and how evidence and context are used and reported in making recommendations.

Peer-reviewed article

Global health Research Designs and Methods: in conversation with Professor Paul Garner

This Podcast features an interview between Professor Paul Garner with Assistant Global Health Professor Eric Green, who discuss the impact of systematic reviews and Cochrane upon evidence-based medicine and evidence-informed guidelines.

Contact tracing strategies in household and congregate environments to identify cases of tuberculosis in low‐ and moderate‐incidence populations

To assess the effectiveness of novel methods of contact tracing versus current standard of care to identify latent and active cases in low‐ to moderate‐incidence settings.

Cochrane Systematic Review: NEW

WHO interim guidelines for the treatment of gambiense human African trypanosomiasis

This document focuses on the management of patients affected by gambiense HAT and constitutes an update to the WHO therapeutic guidance issued in 2013.

Dissemination products

Larviciding to prevent malaria transmission

Evaluating whether larviciding with chemical or microbial insecticides prevents malaria transmission.

Cochrane Systematic Review: NEW

Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations

Esophageal squamous cell carcinoma (ESCC), one of the most aggressive cancers, is endemic in Sub-Saharan Africa, constituting a major health burden.

Peer-reviewed article

Primaquine at alternative dosing schedules for preventing relapse in people with Plasmodium vivax malaria

Primaquine to cure people with Plasmodium vivax malaria: comparing dosing schedules.

Cochrane Systematic Review: NEW

Artemether for severe malaria

Artemether injection for treating people with severe malaria

Cochrane Systematic Review: UPDATE

Rapid initiation of antiretroviral therapy for people living with HIV

To assess the effects of rapid initiation of ART (defined as offering ART within seven days of HIV diagnosis) on treatment outcomes and mortality in people living with HIV (PLWH). We also aim to describe the characteristics of rapid ART interventions used in the included studies.

Cochrane Systematic Review: NEW

A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks—results from the Lassa fever pilot

Infectious disease epidemics are a constant threat, and while we can strengthen preparedness in advance, inevitably, we will sometimes be caught unaware by novel outbreaks.

Peer-reviewed article

Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

To determine the diagnostic accuracy of Xpert MTB/RIF and Xpert Ultra for tuberculosis in adults with presumptive PTB, and for rifampicin resistance in adults with presumptive rifampicin‐resistant tuberculosis or MDR‐TB.

Cochrane Systematic Review: UPDATE

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