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Cochrane reviews

Cochrane Reviews from READ-It Partners in the Cochrane Database of Systematic Reviews.

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Tafenoquine for preventing relapse in people with Plasmodium vivax malaria

The aim of this review was to see if tafenoquine could prevent relapses of vivax infections and if this effect is equivalent to that of standard‐dose primaquine.

Cochrane Systematic Review: UPDATE

Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children

The aim of this review is to determine the accuracy of tests in symptomatic children for diagnosing pulmonary tuberculosis, tuberculous meningitis, lymph node tuberculosis, and rifampicin resistance.

Cochrane Systematic Review: NEW

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Intermittent preventive treatment for malaria in infants

Intermittent preventive treatment could help prevent malaria in infants (IPTi) living in areas of moderate to high malaria transmission in sub‐Saharan Africa.

Cochrane Systematic Review: NEW

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related disease in females and males

Evaluating the efficacy, immunogenicity, and harms of different dose schedules and different types of HPV vaccines in females and males.

Cochrane Systematic Review: NEW

Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations

Most studies evaluating the effect of Xpert MTB/RIF testing for tuberculosis (TB) concluded that it did not reduce overall mortality compared to usual care.

Peer-reviewed article

Lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis of active tuberculosis in people living with HIV Policy update (2019)

The Global TB Programme convened a GDG meeting on 14–16 May 2019, in Geneva, Switzerland, to review the evidence for the use of LF-LAM.

Dissemination products

Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV

This review update asks the question, "does new evidence justify the use of LF‐LAM in a broader group of people?”, and is part of the WHO process for updating guidance on the use of LF‐LAM.

Cochrane Systematic Review: UPDATE

Influencing the evidence ecosystem – a reflection

Professor Taryn Young's Inaugural lecture at Stellenbosch University on 11th October 2019

Podcast: Xpert MTB/RIF and Xpert Ultra for diagnosing pulmonary tuberculosis and rifampicin resistance in adults

Lead author, David Horne from the University of Washington in Seattle in the USA, sets the scene and tells us what the review found.

Abdominal ultrasound for diagnosing abdominal tuberculosis or disseminated tuberculosis with abdominal involvement in HIV‐positive individuals

To determine the diagnostic accuracy of abdominal ultrasound for detecting abdominal tuberculosis or disseminated tuberculosis with abdominal involvement in HIV‐positive individuals.

Cochrane Systematic Review: NEW

Podcast: Effects of starting antiretroviral therapy within one week of diagnosis on people living with HIV

Lead author, Alberto Mateo from the Liverpool School of Tropical Medicine in the UK, tells us about the evidence base and the findings for this important question.

Interventions to improve disposal of child faeces for preventing diarrhoea and soil‐transmitted helminth infection

Assess the effectiveness of interventions to improve the disposal of child faeces for preventing diarrhoea and STH infections.

Cochrane Systematic Review: NEW

Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas

To summarize the effects of public health programmes to regularly treat all children with deworming drugs on child growth, haemoglobin, cognition, school attendance, school performance, physical fitness, and mortality.

Cochrane Systematic Review: UPDATE

WHO guidance for refugees in camps: systematic review

The circumstances of people living in refugee camps means that they have distinct medical care requirements. Our objective is to describe clinical guidance in published WHO guidelines that refer to people living in refugee camps; and how evidence and context are used and reported in making recommendations.

Peer-reviewed article

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