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WHO Guidelines for malaria

The WHO Guidelines for Malaria bring together the WHO's most up-to-date recommendations for malaria. These guidelines supersede two previous WHO publications: the 'Guidelines for the treatment of malaria, third edition' and the 'Guidelines for malaria vector control'. This version of the Guidelines includes recommendations on two new types of insecticide-treated nets.

Dissemination products

Therapeutics for treating mpox in humans

This new review summarizes evidence on the safety and effectiveness of treatments for mpox in humans,

Cochrane Systematic Review: NEW

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WHO Consolidated guidelines on TB: Module 5: Management of tuberculosis in children and adolescents

These WHO guidelines were published in March 2022, and updated in September 2022.

Dissemination products

Podcast: How accurate are rapid antigen tests for diagnosing COVID-19?

Listen to this podcast on how accurate are rapid antigen tests for diagnosing COVID-19?

Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

The combination of nirmatrelvir with ritonavir (Paxlovid®) is a new medicine developed to treat infection with the SARS‐CoV‐2 virus and aims to avoid severe COVID‐19 in people without symptoms, or those with mild symptoms. This new review assessed the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid®) plus standard of care compared to standard of care with or without placebo, or any other intervention for treating COVID‐19 and for preventing SARS‐CoV‐2 infection

Cochrane Systematic Review: NEW

Truth not Triumph: backstage at CIDG. Valedictory lecture by Professor Paul Garner

Truth not Triumph: backstage at CIDG. Valedictory lecture by Professor Paul Garner

Storyboarding HIV infected young people’s adherence to antiretroviral therapy in lower- to upper middle-income countries: a new-materialist qualitative evidence synthesis

In this qualitative evidence synthesis review, the authors study the complex configuration of different agents that impact therapy adherence of young people living with perinatal infections of HIV.

Peer-reviewed article

Update: Adding rapid diagnostic tests to community‐based programmes for treating malaria

The WHO recommends parasitological testing of all suspected malaria cases using malaria rapid diagnostic tests (mRDTs) or microscopy prior to treatment. This update of a 2013 Cochrane Review examines whether adding mRDTs to community-based malaria programmes improves treatment of people with malaria or fever.

Cochrane Systematic Review: UPDATE

Update: 'Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children'

This review update (original version published 27 August 2020) examines the evidence from the previous review in assessing the diagnostic accuracy of Xpert Ultra for detecting: pulmonary tuberculosis, tuberculous meningitis, lymph node tuberculosis, and rifampicin resistance, in children with presumed tuberculosis.

Cochrane Systematic Review: UPDATE

Identifying and managing problematic trials: a Research Integrity Assessment (RIA) tool for randomized controlled trials in evidence synthesis

Ensuring research integrity of studies included in evidence synthesis is an approach that helps to provide evidence closer to the unbiased truth and improves respect of human rights in evidence synthesis. In this paper, the author team explains the rationale and application of a Research Integrity Assessment tool for randomized controlled trials for the update of a Cochrane Review.

Peer-reviewed article

Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women

In adults, using LSSS instead of regular salt in food probably lowers blood pressure slightly.

Cochrane Systematic Review: NEW

Accuracy of measures for antiretroviral adherence in people living with HIV

Health staff sometimes use questionnaires, counting pills, pharmacy notes, or gadgets to estimate if people with HIV are taking their antiretroviral drugs. None of these approaches were reliable when compared to viral load testing, according to the authors of this new Cochrane review

Cochrane Systematic Review: NEW

Update (22 Jul 2022) Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection

This is the third iteration of this Cochrane living review summarising the accuracy of point‐of‐care antigen tests for detecting current SARS‐CoV‐2 infection. (original version published 26 August 2020).

Cochrane Systematic Review: UPDATE

Podcast: Community views on mass drug administration for filariasis: a qualitative evidence synthesis

Listen to this podcast on community view on mass drug administration (MDA) for filariasis

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