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Cochrane Reviews from READ-It Partners in the Cochrane Database of Systematic Reviews.

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Podcast: How accurate are rapid antigen tests for diagnosing COVID-19?

Listen to this podcast on how accurate are rapid antigen tests for diagnosing COVID-19?

Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

The combination of nirmatrelvir with ritonavir (Paxlovid®) is a new medicine developed to treat infection with the SARS‐CoV‐2 virus and aims to avoid severe COVID‐19 in people without symptoms, or those with mild symptoms. This new review assessed the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid®) plus standard of care compared to standard of care with or without placebo, or any other intervention for treating COVID‐19 and for preventing SARS‐CoV‐2 infection

Cochrane Systematic Review: NEW

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Maintaining relevance in HIV systematic reviews: an evaluation of Cochrane reviews

Research turnover in the HIV field is rapid, and as a result, maintaining high-quality, up-to-date, and relevant systematic reviews is a challenge. One approach is to frequently update published reviews.

Peer-reviewed article

Purposive sampling in a qualitative evidence synthesis: a worked example from a synthesis on parental perceptions of vaccination communication

The objective of this article is to describe the development and application of a sampling framework for a qualitative evidence synthesis on vaccination communication.

Peer-reviewed article

Being HIV positive and staying on antiretroviral therapy in Africa: A qualitative systematic review and theoretical model

This analysis provides a practical theory, arising from thematic synthesis of research, to help understand the dynamics of adherence to ART and engagement in HIV care. This can contribute to the design of service delivery approaches, and informed thinking and action on the part of policy makers, providers, and society: to understand what it is to be HIV-positive in Africa and how attitudes and the health service need to shift to help those with HIV lead ‘normal’ lives.

Peer-reviewed article

Systematic reviews using evidence synthesis methods

Antiamoebic drugs for treating amoebic colitis

This Cochrane Review aims to determine the effectiveness and safety of drugs used to treat people with amoebic colitis, which is an infection of the large intestines caused by the parasite, Entamoeba histolytica. Cochrane researchers searched for all relevant studies to answer this question and included 41 relevant studies in this review.

Cochrane Systematic Review: UPDATE

Credit WHO

Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis

In this Cochrane Review, Cochrane researchers examined the effects of using albendazole alone and albendazole added to antifilarial drugs to treat infected people and people who live in areas with lymphatic filariasis. After searching for relevant trials up to January 2018, we included 13 randomized controlled trials (RCTs), including one cluster‐RCT, with a total of 8713 participants.

Cochrane Systematic Review: UPDATE

Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria

The aim of this Cochrane Review was to find out if the antimalarial drug pyronaridine‐artesunate is effective and safe to treat uncomplicated cases of an important type of malaria (P falciparum). We collected and analysed all relevant studies to answer this question and found 10 studies.

Cochrane Systematic Review: UPDATE

Fly control to prevent diarrhoea in children

To find out if controlling flies can prevent diarrhoea in children under the age of five years.

Cochrane Systematic Review: NEW

Researcher and policymaker dialogue:the Policy BUDDIES Project in Western Cape Province, South Africa

Dialogue and exchange between researchers and policy personnel may increase the use of research evidence in policy

Peer-reviewed article

Piperonyl butoxide (PBO) combined with pyrethroids in insecticide‐treated nets to prevent malaria in Africa

The aim of this Cochrane Review was to find out if pyrethroid‐PBO nets add additional protection against malaria when compared to standard pyrethroid‐only nets.

Cochrane Systematic Review: NEW

Community‐based supplementary feeding for food insecure, vulnerable and malnourished populations – an overview of systematic reviews

Cochrane Systematic Review: NEW

Antiretroviral resistance testing in HIV-positive people

The aim of this review was to find out whether a drug resistance test for people living with HIV (starting antiretroviral therapy (ART) or already on ART but with unsuppressed HIV) would reduce the number of deaths or improve HIV suppression.

Cochrane Systematic Review: NEW

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