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Latest resources

New review: The effect of sample site and collection procedure on identification of SARS‐CoV‐2 infection

The review authors compared the sensitivity of different sampling collection sites and methods for the detection of current SARS‐CoV‐2 infection with any molecular or antigen‐based test.

Cochrane Systematic Review: NEW

Evaluation of a strategic academic-government partnership to advance COVID-19 clinical practice guidelines access and uptake in South Africa

The authors of this publication used Cochrane’s KT Framework to map and analyse COVID-19 response activities instituted by a strategic academic-government partnership to supportEIDMduring the COVID-19 pandemic in South Africa.

Peer-reviewed article

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Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

The combination of nirmatrelvir with ritonavir (Paxlovid®) is a new medicine developed to treat infection with the SARS‐CoV‐2 virus and aims to avoid severe COVID‐19 in people without symptoms, or those with mild symptoms. This new review assessed the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid®) plus standard of care compared to standard of care with or without placebo, or any other intervention for treating COVID‐19 and for preventing SARS‐CoV‐2 infection

Cochrane Systematic Review: NEW

Truth not Triumph: backstage at CIDG. Valedictory lecture by Professor Paul Garner

Truth not Triumph: backstage at CIDG. Valedictory lecture by Professor Paul Garner

Storyboarding HIV infected young people’s adherence to antiretroviral therapy in lower- to upper middle-income countries: a new-materialist qualitative evidence synthesis

In this qualitative evidence synthesis review, the authors study the complex configuration of different agents that impact therapy adherence of young people living with perinatal infections of HIV.

Peer-reviewed article

Update: Adding rapid diagnostic tests to community‐based programmes for treating malaria

The WHO recommends parasitological testing of all suspected malaria cases using malaria rapid diagnostic tests (mRDTs) or microscopy prior to treatment. This update of a 2013 Cochrane Review examines whether adding mRDTs to community-based malaria programmes improves treatment of people with malaria or fever.

Cochrane Systematic Review: UPDATE

Update: 'Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children'

This review update (original version published 27 August 2020) examines the evidence from the previous review in assessing the diagnostic accuracy of Xpert Ultra for detecting: pulmonary tuberculosis, tuberculous meningitis, lymph node tuberculosis, and rifampicin resistance, in children with presumed tuberculosis.

Cochrane Systematic Review: UPDATE

Identifying and managing problematic trials: a Research Integrity Assessment (RIA) tool for randomized controlled trials in evidence synthesis

Ensuring research integrity of studies included in evidence synthesis is an approach that helps to provide evidence closer to the unbiased truth and improves respect of human rights in evidence synthesis. In this paper, the author team explains the rationale and application of a Research Integrity Assessment tool for randomized controlled trials for the update of a Cochrane Review.

Peer-reviewed article

Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women

In adults, using LSSS instead of regular salt in food probably lowers blood pressure slightly.

Cochrane Systematic Review: NEW

Strategies to detect and manage latent tuberculosis infection among household contacts of pulmonary TB patients in high TB burden countries - a systematic review and meta-analysis

The objective of this systematic review was to summarise latent tuberculosis infection (LTBI) management strategies among household contacts of bacteriologically confirmed pulmonary tuberculosis (TB) patients in high-TB burden countries

Peer-reviewed article

Accuracy of measures for antiretroviral adherence in people living with HIV

Health staff sometimes use questionnaires, counting pills, pharmacy notes, or gadgets to estimate if people with HIV are taking their antiretroviral drugs. None of these approaches were reliable when compared to viral load testing, according to the authors of this new Cochrane review

Cochrane Systematic Review: NEW

Update (22 Jul 2022) Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection

This is the third iteration of this Cochrane living review summarising the accuracy of point‐of‐care antigen tests for detecting current SARS‐CoV‐2 infection. (original version published 26 August 2020).

Cochrane Systematic Review: UPDATE

Podcast: Community views on mass drug administration for filariasis: a qualitative evidence synthesis

Listen to this podcast on community view on mass drug administration (MDA) for filariasis

Resources supporting trustworthy, rapid and equitable evidence synthesis and guideline development: results from the COVID-19 evidence network to support decision-making (COVID-END)

COVID-19 and subsequent infodemic represents an unprecedented global challenge for evidence synthesis and guideline development. The authors present consolidated resources to facilitate trustworthy, rapid and equitable evidence synthesis, health technology assessments and guidelines for public health and clinical practice.

Peer-reviewed article

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